Multiple controls regulate nucleostemin partitioning between nucleolus and nucleoplasm
نویسندگان
چکیده
منابع مشابه
Multiple controls regulate nucleostemin partitioning between nucleolus and nucleoplasm.
Nucleostemin plays an essential role in maintaining the continuous proliferation of stem cells and cancer cells. The movement of nucleostemin between the nucleolus and the nucleoplasm provides a dynamic way to partition the nucleostemin protein between these two compartments. Here, we show that nucleostemin contains two nucleolus-targeting regions, the basic and the GTP-binding domains, that ex...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2006
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.03292